Best open-source Python AI agent frameworks

Updated 17 Oct 2026 · Prices from vendor pages only · How we rank →

The short answer

Each of these is a code-first agent framework you can install in Python, with a free open-source or free tier to start. CrewAI comes first: multi-agent orchestration framework plus hosted platform. The cheapest verified paid plan here is LlamaIndex Starter ($50/month). 7 of the 7 have a free plan we could confirm. Every price below is from the vendor’s own page, checked 16–17 Oct 2026.

Ranked shortlist

  1. CrewAI: Multi-agent orchestration framework plus hosted platform. Plan: Basic: Free
    50 executions/month
  2. OpenAI Agents SDK: OpenAI's lightweight framework for multi-agent workflows. Plan: Open source (MIT)
  3. Google ADK: Google's open-source Agent Development Kit. Plan: Open source (Apache-2.0)
  4. Microsoft Agent Framework: Microsoft's open-source successor to AutoGen and Semantic Kernel agents. Plan: Open source (MIT)
  5. LlamaIndex: Framework and cloud for agents over your documents. Plan: Free: $0/month
  6. Pydantic AI: Type-safe Python agent framework from the Pydantic team. Plan: Open source (MIT)
  7. Agno: Open-source Python framework and runtime for multi-agent systems. Plan: Free: $0/month

Order follows ToolRank’s editorial ranking in Automation & Agents, filtered to tools that fit this page. Anything we couldn’t confirm on a vendor page says “Not yet verified”.

Side by side

RankToolRelevant planStarting priceFree planBest forMain limitationLast checked
#1CrewAIBasic: Free
50 executions/month
Not yet verifiedBasic: free, 50 workflow executions/monthDevelopers building multi-agent workflowsPaid self-serve tier not shown; Enterprise is custom16 Oct 2026
#2OpenAI Agents SDKOpen source (MIT)Not yet verifiedOpen source (MIT)Developers building multi-agent workflows with tools and handoffsYou pay your model provider for usage17 Oct 2026
#3Google ADKOpen source (Apache-2.0)Not yet verifiedOpen source (Apache-2.0)Developers building agents on Gemini and Google CloudYou pay your model provider for usage17 Oct 2026
#4Microsoft Agent FrameworkOpen source (MIT)Not yet verifiedOpen source (MIT).NET and Python teams taking agents to production on Microsoft's stackYou pay your model provider for usage17 Oct 2026
#5LlamaIndexFree: $0/month$50/month (Starter)Free: $0/monthDocument parsing and retrieval for LLM appsCloud credits limit parsing volume16 Oct 2026
#6Pydantic AIOpen source (MIT)Not yet verifiedOpen source (MIT)Python developers who want type-safe agentsA code library: you supply model API keys and hosting17 Oct 2026
#7AgnoFree: $0/month$150/month (Pro)Free: $0/month runtime, you host itPython developers running agents on their own infrastructureControl plane needs Pro16 Oct 2026

Prices as listed by each vendor on the last-checked date, USD, before tax. Plans and limits change, so follow the sources below.

Who should pick which

Pick CrewAI for developers building multi-agent workflows (Basic: Free). Watch out: paid self-serve tier not shown; Enterprise is custom. Pick OpenAI Agents SDK for developers building multi-agent workflows with tools and handoffs (free plan: Open source (MIT)). Watch out: you pay your model provider for usage. Pick Google ADK for developers building agents on Gemini and Google Cloud (free plan: Open source (Apache-2.0)). Watch out: you pay your model provider for usage. Pick Microsoft Agent Framework for .NET and Python teams taking agents to production on Microsoft's stack (free plan: Open source (MIT)). Watch out: you pay your model provider for usage. Pick LlamaIndex for document parsing and retrieval for LLM apps (Free: $0/month). Watch out: cloud credits limit parsing volume. Pick Pydantic AI for python developers who want type-safe agents (free plan: Open source (MIT)). Watch out: a code library: you supply model API keys and hosting. Pick Agno for python developers running agents on their own infrastructure (Free: $0/month). Watch out: control plane needs Pro.

FAQ

Which of these is cheapest?

LlamaIndex Starter ($50/month) is the lowest paid price we verified on this list (https://www.llamaindex.ai/pricing, checked 16 Oct 2026). Check the vendor page for tax, billing period and usage limits.

Which of these have a free plan?

CrewAI: Basic: free, 50 workflow executions/month; OpenAI Agents SDK: Open source (MIT); Google ADK: Open source (Apache-2.0); Microsoft Agent Framework: Open source (MIT); LlamaIndex: Free: $0/month; Pydantic AI: Open source (MIT); Agno: Free: $0/month runtime, you host it.

How were these tools chosen?

They are the tools in ToolRank's rankings with a Python framework listed on the vendor's site or repository, confirmed on the vendor's own website on 16–17 Oct 2026. Tools we could not verify are left out rather than guessed, and anything unconfirmed is marked Not yet verified.

Sources

Related comparisons

Profiles: CrewAI · OpenAI Agents SDK · Google ADK · Microsoft Agent Framework · LlamaIndex · Pydantic AI · Agno

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